×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

1 keywords

CATH Domain 4k94H02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

P10721
KIT_HUMAN
Homo sapiens
Mast/stem cell growth factor receptor Kit

PDB Structure

PDB 4K94
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for KIT receptor tyrosine kinase inhibition by antibodies targeting the D4 membrane-proximal region.
Reshetnyak, A.V., Nelson, B., Shi, X., Boggon, T.J., Pavlenco, A., Mandel-Bausch, E.M., Tome, F., Suzuki, Y., Sidhu, S.S., Lax, I., Schlessinger, J.
Proc.Natl.Acad.Sci.USA
CATH-Gene3D is a Global Biodata Core Resource Learn more...