CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | Immunoglobulin heavy constant gamma 1 |
Enzyme Information
UniProtKB Entries (0)
PDB Structure
| PDB | 4JY4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Plos Pathog.
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