1 keywords

CATH Domain 4jy4A01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family

Enzyme Information

UniProtKB Entries (0)

PDB Structure

PDB 4JY4
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Broadly neutralizing antibody PGT121 allosterically modulates CD4 binding via recognition of the HIV-1 gp120 V3 base and multiple surrounding glycans.
Julien, J.P., Sok, D., Khayat, R., Lee, J.H., Doores, K.J., Walker, L.M., Ramos, A., Diwanji, D.C., Pejchal, R., Cupo, A., Katpally, U., Depetris, R.S., Stanfield, R.L., McBride, R., Marozsan, A.J., Paulson, J.C., Sanders, R.W., Moore, J.P., Burton, D.R., Poignard, P., Ward, A.B., Wilson, I.A.
Plos Pathog.