1 keywords

CATH Domain 4jm2B01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin kappa chain variable 18-36

Enzyme Information

UniProtKB Entries (2)

P01730
CD4_HUMAN
Homo sapiens
T-cell surface glycoprotein CD4
Q75760
Q75760_9HIV1
Human immunodeficiency virus 1
Envelope glycoprotein gp160

PDB Structure

PDB 4JM2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Supersite of immune vulnerability on the glycosylated face of HIV-1 envelope glycoprotein gp120.
Kong, L., Lee, J.H., Doores, K.J., Murin, C.D., Julien, J.P., McBride, R., Liu, Y., Marozsan, A., Cupo, A., Klasse, P.J., Hoffenberg, S., Caulfield, M., King, C.R., Hua, Y., Le, K.M., Khayat, R., Deller, M.C., Clayton, T., Tien, H., Feizi, T., Sanders, R.W., Paulson, J.C., Moore, J.P., Stanfield, R.L., Burton, D.R., Ward, A.B., Wilson, I.A.
Nat.Struct.Mol.Biol.