CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.10 | Arc Repressor Mutant, subunit A |
|
1.10.10.10 | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
Domain Context
CATH Clusters
| Superfamily | Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain |
| Functional Family | Friend leukemia integration 1 transcription factor |
Enzyme Information
UniProtKB Entries (1)
| P11308 |
ERG_HUMAN
Homo sapiens
Transcriptional regulator ERG
|
PDB Structure
| PDB | 4IRH |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Proc.Natl.Acad.Sci.USA
|
