1 keywords

CATH Domain 4heeX00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Peroxisome proliferator-activated receptor gamma

Enzyme Information

UniProtKB Entries (1)

Q15788
NCOA1_HUMAN
Homo sapiens
Nuclear receptor coactivator 1

PDB Structure

PDB 4HEE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design, synthesis, and evaluation of imidazo[4,5-c]pyridin-4-one derivatives with dual activity at angiotensin II type 1 receptor and peroxisome proliferator-activated receptor-gamma
Casimiro-Garcia, A., Heemstra, R.J., Bigge, C.F., Chen, J., Ciske, F.A., Davis, J.A., Ellis, T., Esmaeil, N., Flynn, D., Han, S., Jalaie, M., Ohren, J.F., Powell, N.A.
Bioorg.Med.Chem.Lett.