CATH Domain 4gv0A01

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.20	Up-down Bundle
	1.20.142	Poly(ADP-ribose) Polymerase; domain 1
	1.20.142.10	Poly(ADP-ribose) polymerase, regulatory domain

Domain Context

CATH Clusters

Superfamily	Poly(ADP-ribose) polymerase, regulatory domain
Functional Family	Poly [ADP-ribose] polymerase

Enzyme Information

2.4.2.-

Pentosyltransferases.

based on mapping to UniProt Q9Y6F1

UniProtKB Entries (1)

PARP3_HUMAN

Homo sapiens

Protein mono-ADP-ribosyltransferase PARP3

PDB Structure

PDB	4GV0
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3 Lindgren, A.E.G., Karlberg, T., Thorsell, A.G., Hesse, M., Spjut, S., Ekblad, T., Andersson, C.D., Pinto, A.F., Weigelt, J., Hottiger, M.O., Linusson, A., Elofsson, M., Schuler, H. Acs Chem.Biol.