CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.30 | 2-Layer Sandwich |
|
3.30.420 | Nucleotidyltransferase; domain 5 |
|
3.30.420.10 | Ribonuclease H-like superfamily/Ribonuclease H |
Domain Context
CATH Clusters
| Superfamily | Ribonuclease H-like superfamily/Ribonuclease H |
| Functional Family | CCR4-NOT transcription complex subunit 7 |
Enzyme Information
| 3.1.13.4 |
Poly(A)-specific ribonuclease.
based on mapping to UniProt Q9UIV1
Exonucleolytic cleavage of poly(A) to 5'-AMP.
-!- Cleaves poly(A) in either the single- or double-stranded form.
|
UniProtKB Entries (1)
| A5YKK6 |
CNOT1_HUMAN
Homo sapiens
CCR4-NOT transcription complex subunit 1
|
PDB Structure
| PDB | 4GMJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The structural basis for the interaction between the CAF1 nuclease and the NOT1 scaffold of the human CCR4-NOT deadenylase complex
Nucleic Acids Res.
|