CATH Domain 4g5dA00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.100	NADP-dependent oxidoreductase domain

Domain Context

CATH Clusters

Superfamily	NADP-dependent oxidoreductase domain
Functional Family

Enzyme Information

1.1.1.-

With NAD(+) or NADP(+) as acceptor.

based on mapping to UniProt P22045

UniProtKB Entries (1)

PGFS_LEIMA

Leishmania major

9,11-endoperoxide prostaglandin H2 reductase

PDB Structure

PDB	4G5D
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structures of prostaglandin F synthase from the protozoa Leishmania major and Trypanosoma cruzi with NADP. Moen, S.O., Fairman, J.W., Barnes, S.R., Sullivan, A., Nakazawa-Hewitt, S., Van Voorhis, W.C., Staker, B.L., Lorimer, D.D., Myler, P.J., Edwards, T.E. Acta Crystallogr F Struct Biol Commun