CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P04049
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P01112
RASH_HUMAN
Homo sapiens
GTPase HRas

PDB Structure

PDB 4G3X
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD.
Fetics, S.K., Guterres, H., Kearney, B.M., Buhrman, G., Ma, B., Nussinov, R., Mattos, C.
Structure