CATH Domain 4g3mB02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.430	Dihydrofolate Reductase, subunit A
	3.40.430.10	Dihydrofolate Reductase, subunit A

Domain Context

CATH Clusters

Superfamily	Dihydrofolate Reductase, subunit A
Functional Family	Riboflavin biosynthesis protein RibD

Enzyme Information

1.1.1.193	5-amino-6-(5-phosphoribosylamino)uracil reductase. based on mapping to UniProt P17618 5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6- (5-phospho-D-ribosylamino)uracil + NADPH.
3.5.4.26	Diaminohydroxyphosphoribosylaminopyrimidine deaminase. based on mapping to UniProt P17618 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine + H(2)O = 5-amino-6-(5-phosphoribosylamino)uracil + NH(3). -!- The substrate is the product of EC 3.5.4.25.

UniProtKB Entries (1)

RIBD_BACSU

Bacillus subtilis subsp. subtilis str. 168

Riboflavin biosynthesis protein RibD

PDB Structure

PDB	4G3M
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Evolution of vitamin B(2) biosynthesis: eubacterial RibG and fungal Rib2 deaminases. Chen, S.C., Shen, C.Y., Yen, T.M., Yu, H.C., Chang, T.H., Lai, W.L., Liaw, S.H. Acta Crystallogr.,Sect.D