CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.1280.10
Functional Family Ribosomal RNA small subunit methyltransferase E

Enzyme Information

2.1.1.193
16S rRNA (uracil(1498)-N(3))-methyltransferase.
based on mapping to UniProt P0AGL7
S-adenosyl-L-methionine + uracil(1498) in 16S rRNA = S-adenosyl-L- homocysteine + N(3)-methyluracil(1498) in 16S rRNA.
-!- The enzyme specifically methylates uracil(1498) at N(3) in 16S rRNA.

UniProtKB Entries (1)

P0AGL7
RSME_ECOLI
Escherichia coli K-12
Ribosomal RNA small subunit methyltransferase E

PDB Structure

PDB 4E8B
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Insights into the catalytic mechanism of 16S rRNA methyltransferase RsmE (m(3)U1498) from crystal and solution structures
Zhang, H., Wan, H., Gao, Z.Q., Wei, Y., Wang, W.J., Liu, G.F., Shtykova, E.V., Xu, J.H., Dong, Y.H.
J.Mol.Biol.
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