1 keywords

CATH Domain 4dtgL01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family If kappa light chain

Enzyme Information

UniProtKB Entries (1)

P10646
TFPI1_HUMAN
Homo sapiens
Tissue factor pathway inhibitor

PDB Structure

PDB 4DTG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Hemostatic effect of a monoclonal antibody mAb 2021 blocking the interaction between FXa and TFPI in a rabbit hemophilia model.
Hilden, I., Lauritzen, B., Sorensen, B.B., Clausen, J.T., Jespersgaard, C., Krogh, B.O., Bowler, A.N., Breinholt, J., Gruhler, A., Svensson, L.A., Petersen, H.H., Petersen, L.C., Balling, K.W., Hansen, L., Hermit, M.B., Egebjerg, T., Friederichsen, B., Ezban, M., Bjorn, S.E.
Blood