CATH Domain 4dkkA02

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.160	Double Stranded RNA Binding Domain
	3.30.160.20

Domain Context

CATH Clusters

Superfamily	3.30.160.20
Functional Family	double-stranded RNA-binding protein Staufen homolog 1 isoform X1

Enzyme Information

UniProtKB Entries (1)

STAU1_HUMAN

Homo sapiens

Double-stranded RNA-binding protein Staufen homolog 1

PDB Structure

PDB	4DKK
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Staufen1 dimerizes through a conserved motif and a degenerate dsRNA-binding domain to promote mRNA decay. Gleghorn, M.L., Gong, C., Kielkopf, C.L., Maquat, L.E. Nat.Struct.Mol.Biol.