CATH Domain 4d1tA00

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CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.60	4-Layer Sandwich
	3.60.15	Metallo-beta-lactamase; Chain A
	3.60.15.10	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like

Domain Context

CATH Clusters

Superfamily	Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Functional Family

Enzyme Information

UniProtKB Entries (1)

Q840P9_PSEAI

Pseudomonas aeruginosa

Metallo-b-lactamase

PDB Structure

PDB	4D1T
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	His224 Alters the R2 Drug Binding Site and Phe218 Influences the Catalytic Efficiency in the Metallo-Beta-Lactamase Vim-7. Leiros, H.-K.S., Skagseth, S., Edvardsen, K.S.W., Lorentzen, M.S., Bjerga, G.E.K., Leiros, I., Samuelsen, O. Antimicrob.Agents Chemother.