CATH Domain 4cstA00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1090	Fimbrial-type adhesion domain

Domain Context

CATH Clusters

Superfamily	Fimbrial-type adhesion domain
Functional Family	Type 1 fimbrin D-mannose specific adhesin

Enzyme Information

UniProtKB Entries (1)

FIMH_ECOLI

Escherichia coli K-12

Type 1 fimbrin D-mannose specific adhesin

PDB Structure

PDB	4CST
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Fimh Antagonists: Bioisosteres to Improve the in Vitro and in Vivo Pk/Pd Profile. Ernst, B., Kleeb, S., Pang, L., Mayer, K., Eris, D., Sigl, A., Zihlmann, P., Preston, R.C., Sharpe, T., Jakob, R., Abgottspon, D., Hutter, A.S., Scharenberg, M., Jiang, X., Navarra, G., Rabbani, S., Smiesko, M., Ludin, N., Bezencon, J., Schwardt, O., Maier, T. J.Med.Chem.