CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.130 | 7 Propeller |
|
2.130.10 | Methylamine Dehydrogenase; Chain H |
|
2.130.10.10 | YVTN repeat-like/Quinoprotein amine dehydrogenase |
Domain Context
CATH Clusters
| Superfamily | YVTN repeat-like/Quinoprotein amine dehydrogenase |
| Functional Family | DDB1 and CUL4-associated factor 1 |
Enzyme Information
| 2.7.11.1 |
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9Y4B6
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.
|
UniProtKB Entries (2)
| Q9Y3Z3 |
SAMH1_HUMAN
Homo sapiens
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1
|
| P19508 |
VPX_SIVSP
Simian immunodeficiency virus (PBJ/BC13 ISOLATE) (SOOTY MANGABEY)
Protein Vpx
|
PDB Structure
| PDB | 4CC9 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structural Basis of Lentiviral Subversion of a Cellular Protein Degradation Pathway.
Nature
|
