CATH Domain 4bsrD00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.10	Ribbon
	2.10.220	Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A domain 2
	2.10.220.10	Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2

Domain Context

CATH Clusters

Superfamily	Hormone Receptor, Insulin-like Growth Factor Receptor 1; Chain A, domain 2
Functional Family	R-spondin 3

Enzyme Information

UniProtKB Entries (1)

LGR5_HUMAN

Homo sapiens

Leucine-rich repeat-containing G-protein coupled receptor 5

PDB Structure

PDB	4BSR
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Structure of Stem Cell Growth Factor R-Spondin 1 in Complex with the Ectodomain of its Receptor Lgr5. Peng, W.C., De Lau, W., Forneris, F., Granneman, J.C.M., Huch, M., Clevers, H., Gros, P. Cell Rep.