CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1320.30
Functional Family Probable ATP-dependent RNA helicase DDX58

Enzyme Information

3.6.4.13
RNA helicase.
based on mapping to UniProt O95786
ATP + H(2)O = ADP + phosphate.
-!- RNA helicases utilize the energy from ATP hydrolysis to unwind RNA. -!- Some of them unwind RNA with a 3' to 5' polarity, other show 5' to 3' polarity. -!- Some helicases unwind DNA as well as RNA. -!- May be identical with EC 3.6.4.12 (DNA helicase).

UniProtKB Entries (1)

O95786
DDX58_HUMAN
Homo sapiens
Probable ATP-dependent RNA helicase DDX58

PDB Structure

PDB 4AY2
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Visualizing the Determinants of Viral RNA Recognition by Innate Immune Sensor Rig-I.
Luo, D., Kohlway, A., Vela, A., Pyle, A.M.
Structure
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