1 keywords

CATH Domain 4afuA01

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.40 Beta Barrel
Topology 2.40.10 Thrombin, subunit H
Homologous Superfamily 2.40.10.10 Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily Trypsin-like serine proteases
Functional Family Complement factor D

Enzyme Information

3.4.21.39
Chymase.
based on mapping to UniProt P23946
Preferential cleavage: Phe-|-Xaa > Tyr-|-Xaa > Trp-|-Xaa > Leu-|-Xaa.
-!- In mast cell granules. -!- Belongs to peptidase family S1.

UniProtKB Entries (1)

P23946
CMA1_HUMAN
Homo sapiens
Chymase

PDB Structure

PDB 4AFU
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Generation, Characterization and Structural Data of Chymase Binding Proteins Based on the Human Fyn Kinase SH3 Domain.
Schlatter, D., Brack, S., Banner, D.W., Batey, S., Benz, J., Bertschinger, J., Huber, W., Joseph, C., Rufer, A., Van Der Klooster, A., Weber, M., Grabulovski, D., Hennig, M.
Mabs