CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.300 | P-loop containing nucleotide triphosphate hydrolases |
Domain Context
CATH Clusters
| Superfamily | P-loop containing nucleotide triphosphate hydrolases |
| Functional Family | Dynamin-1-like protein isoform 1 |
Enzyme Information
| 3.6.5.5 |
Dynamin GTPase.
based on mapping to UniProt O00429
GTP + H(2)O = GDP + phosphate.
-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.
|
UniProtKB Entries (1)
| O00429 |
DNM1L_HUMAN
Homo sapiens
Dynamin-1-like protein
|
PDB Structure
| PDB | 3W6N |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of GTPase domain fused with minimal stalks from human dynamin-1-like protein (Dlp1) in complex with several nucleotide analogues
CURR TOP PEPT PROTEIN RES.
|
