CATH Classification
Level | CATH Code | Description |
---|---|---|
2 | Mainly Beta | |
2.70 | Distorted Sandwich | |
2.70.98 | Beta-galactosidase; Chain A, domain 5 | |
2.70.98.10 |
Domain Context
CATH Clusters
Superfamily | 2.70.98.10 |
Functional Family | Beta-galactosidase |
Enzyme Information
3.2.1.23 |
Beta-galactosidase.
based on mapping to UniProt P00722
Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D- galactosides.
-!- Some enzymes in this group hydrolyze alpha-L-arabinosides; some animal enzymes also hydrolyze beta-D-fucosides and beta-D-glucosides (cf. EC 3.2.1.108).
|
UniProtKB Entries (1)
P00722 |
BGAL_ECOLI
Escherichia coli K-12
Beta-galactosidase
|
PDB Structure
PDB | 3VD4 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Substitution for Asn460 cripples {beta}-galactosidase (Escherichia coli) by increasing substrate affinity and decreasing transition state stability.
Arch.Biochem.Biophys.
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