1 keywords

CATH Domain 3uezH00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.1250 Growth Hormone; Chain: A;
Homologous Superfamily 1.20.1250.10  

Domain Context

CATH Clusters

Superfamily 1.20.1250.10
Functional Family Macrophage colony-stimulating factor 1

Enzyme Information

UniProtKB Entries (2)

P03228
BARF1_EBVB9
Human herpesvirus 4 strain B95-8
Secreted protein BARF1
P09603
CSF1_HUMAN
Homo sapiens
Macrophage colony-stimulating factor 1

PDB Structure

PDB 3UEZ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Allosteric competitive inactivation of hematopoietic CSF-1 signaling by the viral decoy receptor BARF1
Elegheert, J., Bracke, N., Pouliot, P., Gutsche, I., Shkumatov, A.V., Tarbouriech, N., Verstraete, K., Bekaert, A., Burmeister, W.P., Svergun, D.I., Lambrecht, B.N., Vergauwen, B., Savvides, S.N.
Nat.Struct.Mol.Biol.