CATH Classification

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family T-cell immunoreceptor with Ig and ITIM domains

Enzyme Information

UniProtKB Entries (1)

Q495A1
TIGIT_HUMAN
Homo sapiens
T-cell immunoreceptor with Ig and ITIM domains

PDB Structure

PDB 3UCR
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering.
Stengel, K.F., Harden-Bowles, K., Yu, X., Rouge, L., Yin, J., Comps-Agrar, L., Wiesmann, C., Bazan, J.F., Eaton, D.L., Grogan, J.L.
Proc.Natl.Acad.Sci.USA