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1 keywords

CATH Domain 3sqoH02

CATH Classification

Level CATH Code Description
Class 2 Mainly Beta
Architecture 2.60 Sandwich
Topology 2.60.40 Immunoglobulin-like
Homologous Superfamily 2.60.40.10 Immunoglobulins

Domain Context

CATH Clusters

Superfamily Immunoglobulins
Functional Family Immunoglobulin heavy constant gamma 1

Enzyme Information

UniProtKB Entries (1)

Q8NBP7
PCSK9_HUMAN
Homo sapiens
Proprotein convertase subtilisin/kexin type 9

PDB Structure

PDB 3SQO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primates.
Liang, H., Chaparro-Riggers, J., Strop, P., Geng, T., Sutton, J.E., Tsai, D., Bai, L., Abdiche, Y., Dilley, J., Yu, J., Wu, S., Chin, S.M., Lee, N.A., Rossi, A., Lin, J.C., Rajpal, A., Pons, J., Shelton, D.L.
J.Pharmacol.Exp.Ther.
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