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1 keywords

CATH Domain 3spfA00

Note: The assignment for domain 3spfA00 was not available when the latest CATH+ database (v4_4_0) was released. The information below comes from putative assignments made in our daily snapshot: CATH-B. These assignments have gone through fewer checks than information from a CATH+ release.

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.437 Apoptosis Regulator Bcl-x
Homologous Superfamily 1.10.437.10 Blc2-like

Domain Context

CATH Clusters

Superfamily
Functional Family -

PDB Structure

PDB 3SPF
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Design of Bcl-2 and Bcl-xL Inhibitors with Subnanomolar Binding Affinities Based upon a New Scaffold.
Zhou, H., Chen, J., Meagher, J.L., Yang, C.Y., Aguilar, A., Liu, L., Bai, L., Cong, X., Cai, Q., Fang, X., Stuckey, J.A., Wang, S.
J.Med.Chem.
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