×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily P-loop containing nucleotide triphosphate hydrolases
Functional Family dynamin-1 isoform X2

Enzyme Information

3.6.5.5
Dynamin GTPase.
based on mapping to UniProt Q05193
GTP + H(2)O = GDP + phosphate.
-!- An enzyme with a molecular mass of about 100 kDa that is involved in endocytosis and is instrumental in pinching off membrane vesicles. -!- Formerly EC 3.6.1.50.

UniProtKB Entries (1)

Q05193
DYN1_HUMAN
Homo sapiens
Dynamin-1

PDB Structure

PDB 3SNH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of nucleotide-free dynamin.
Faelber, K., Posor, Y., Gao, S., Held, M., Roske, Y., Schulze, D., Haucke, V., Noe, F., Daumke, O.
Nature
CATH-Gene3D is a Global Biodata Core Resource Learn more...