CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphatidylinositol (PI) phosphodiesterase
Functional Family

Enzyme Information

UniProtKB Entries (1)

F2YQ19
F2YQ19_SEPOF
Sepia officinalis
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase

PDB Structure

PDB 3QR0
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
An autoinhibitory helix in the C-terminal region of phospholipase C-beta mediates Galphaq activation.
Lyon, A.M., Tesmer, V.M., Dhamsania, V.D., Thal, D.M., Gutierrez, J., Chowdhury, S., Suddala, K.C., Northup, J.K., Tesmer, J.J.
Nat.Struct.Mol.Biol.