CATH Domain 3q43A04

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.60	Sandwich
	2.60.40	Immunoglobulin-like
	2.60.40.1840	Aminopeptidase N, middle-beta domain

Domain Context

CATH Clusters

Superfamily	2.60.40.1840
Functional Family	Aminopeptidase N

Enzyme Information

3.4.11.-

Aminopeptidases.

based on mapping to UniProt O96935

UniProtKB Entries (1)

AMP1_PLAFQ

Plasmodium falciparum FcB1/Columbia

M1 family aminopeptidase

PDB Structure

PDB	3Q43
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Synthesis of new (-)-bestatin-based inhibitor libraries reveals a novel binding mode in the s1 pocket of the essential malaria m1 metalloaminopeptidase. Velmourougane, G., Harbut, M.B., Dalal, S., McGowan, S., Oellig, C.A., Meinhardt, N., Whisstock, J.C., Klemba, M., Greenbaum, D.C. J.Med.Chem.