×

Network disruptions

We have been experiencing disruptions on our local network which has affected the stability of these web pages. We have been working with IT support team to get this fixed as a matter of urgency and apologise for any inconvenience.

CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.70.80
Functional Family RNA-directed RNA polymerase L

Enzyme Information

UniProtKB Entries (2)

P05161
ISG15_HUMAN
Homo sapiens
Ubiquitin-like protein ISG15
Q6TQF5
Q6TQF5_9VIRU
Crimean-Congo hemorrhagic fever orthonairovirus
Putative RNA polymerase

PDB Structure

PDB 3PSE
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
James, T.W., Frias-Staheli, N., Bacik, J.P., Levingston Macleod, J.M., Khajehpour, M., Garcia-Sastre, A., Mark, B.L.
Proc.Natl.Acad.Sci.USA
CATH-Gene3D is a Global Biodata Core Resource Learn more...