CATH Classification

Domain Context

CATH Clusters

Superfamily Ribonuclease Inhibitor
Functional Family Platelet glycoprotein Ib alpha chain

Enzyme Information

UniProtKB Entries (1)

P00734
THRB_HUMAN
Homo sapiens
Prothrombin

PDB Structure

PDB 3PMH
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Binding of alpha-thrombin to surface-anchored platelet glycoprotein Ib(alpha) sulfotyrosines through a two-site mechanism involving exosite I.
Zarpellon, A., Celikel, R., Roberts, J.R., McClintock, R.A., Mendolicchio, G.L., Moore, K.L., Jing, H., Varughese, K.I., Ruggeri, Z.M.
Proc.Natl.Acad.Sci.USA