CATH Domain 3pl7B00

Note: The assignment for domain 3pl7B00 was not available when the latest CATH+ database (v4_3_0) was released. The information below comes from putative assignments made in our daily snapshot: CATH-B. These assignments have gone through fewer checks than information from a CATH+ release.

CATH Classification

Level	CATH Code	Description
	1	Mainly Alpha
	1.10	Orthogonal Bundle
	1.10.437	Apoptosis Regulator Bcl-x
	1.10.437.10	Blc2-like

Domain Context

CATH Clusters

Superfamily
Functional Family	-

PDB Structure

PDB	3PL7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mutation to Bax beyond the BH3 domain disrupts interactions with pro-survival proteins and promotes apoptosis Czabotar, P.E., Lee, E.F., Thompson, G.V., Wardak, A.Z., Fairlie, W.D., Colman, P.M. J.Biol.Chem.