CATH Domain 3pe6A00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.40	3-Layer(aba) Sandwich
	3.40.50	Rossmann fold
	3.40.50.1820	alpha/beta hydrolase

Domain Context

CATH Clusters

Superfamily	alpha/beta hydrolase
Functional Family	Monoglyceride lipase

Enzyme Information

3.1.1.23

Acylglycerol lipase.

based on mapping to UniProt Q99685

Hydrolyzes glycerol monoesters of long-chain fatty acids.

UniProtKB Entries (1)

MGLL_HUMAN

Homo sapiens

Monoglyceride lipase

PDB Structure

PDB	3PE6
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Crystal structure of a soluble form of human monoglyceride lipase in complex with an inhibitor at 1.35 A resolution. Schalk-Hihi, C., Schubert, C., Alexander, R., Bayoumy, S., Clemente, J.C., Deckman, I., DesJarlais, R.L., Dzordzorme, K.C., Flores, C.M., Grasberger, B., Kranz, J.K., Lewandowski, F., Liu, L., Ma, H., Maguire, D., Macielag, M.J., McDonnell, M.E., Mezzasalma Haarlander, T., Miller, R., Milligan, C., Reynolds, C., Kuo, L.C. Protein Sci.