1 keywords

CATH Domain 3p89A00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.10 Orthogonal Bundle
Topology 1.10.565 Retinoid X Receptor
Homologous Superfamily 1.10.565.10 Retinoid X Receptor

Domain Context

CATH Clusters

Superfamily Retinoid X Receptor
Functional Family Bile acid receptor isoform 4

Enzyme Information

UniProtKB Entries (1)

Q15788
NCOA1_HUMAN
Homo sapiens
Nuclear receptor coactivator 1

PDB Structure

PDB 3P89
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Conformationally constrained farnesoid X receptor (FXR) agonists: Heteroaryl replacements of the naphthalene.
Bass, J.Y., Caravella, J.A., Chen, L., Creech, K.L., Deaton, D.N., Madauss, K.P., Marr, H.B., McFadyen, R.B., Miller, A.B., Mills, W.Y., Navas, F., Parks, D.J., Smalley, T.L., Spearing, P.K., Todd, D., Williams, S.P., Wisely, G.B.
Bioorg.Med.Chem.Lett.