CATH Classification

Domain Context

CATH Clusters

Superfamily TAZ domain
Functional Family E1A binding protein p300

Enzyme Information

2.3.1.48
Histone acetyltransferase.
based on mapping to UniProt Q09472
Acetyl-CoA + [protein]-L-lysine = CoA + [protein]-N(6)-acetyl-L-lysine.
-!- A group of enzymes acetylating histones. -!- Several of the enzymes can also acetylate lysines in other proteins.
2.3.1.-
Transferring groups other than amino-acyl groups.
based on mapping to UniProt Q09472

UniProtKB Entries (1)

Q02078
MEF2A_HUMAN
Homo sapiens
Myocyte-specific enhancer factor 2A

PDB Structure

PDB 3P57
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structure of p300 bound to MEF2 on DNA reveals a mechanism of enhanceosome assembly.
He, J., Ye, J., Cai, Y., Riquelme, C., Liu, J.O., Liu, X., Han, A., Chen, L.
Nucleic Acids Res.
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