CATH Classification

Domain Context

CATH Clusters

Superfamily Nucleoside phosphorylase domain
Functional Family Uridine phosphorylase 2

Enzyme Information

2.4.2.3
Uridine phosphorylase.
based on mapping to UniProt O95045
Uridine + phosphate = uracil + alpha-D-ribose 1-phosphate.
-!- The enzyme participates the the pathways of pyrimidine ribonucleosides degradation and salvage. -!- The mammalian enzyme also accepts 2'-deoxyuridine. -!- Formerly EC 2.4.2.23.

UniProtKB Entries (1)

O95045
UPP2_HUMAN
Homo sapiens
Uridine phosphorylase 2

PDB Structure

PDB 3P0F
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
A novel structural mechanism for redox regulation of uridine phosphorylase 2 activity.
Roosild, T.P., Castronovo, S., Villoso, A., Ziemba, A., Pizzorno, G.
J.Struct.Biol.