CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.5.340
Functional Family Rho-associated protein kinase 1

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q13464
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q13464
ROCK1_HUMAN
Homo sapiens
Rho-associated protein kinase 1

PDB Structure

PDB 3O0Z
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal Structure of a Coiled-Coil Domain from Human ROCK I.
Tu, D., Li, Y., Song, H.K., Toms, A.V., Gould, C.J., Ficarro, S.B., Marto, J.A., Goode, B.L., Eck, M.J.
Plos One