CATH Domain 3nziA02

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CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.40	Beta Barrel
	2.40.10	Thrombin, subunit H
	2.40.10.10	Trypsin-like serine proteases

Domain Context

CATH Clusters

Superfamily	Trypsin-like serine proteases
Functional Family

Enzyme Information

3.4.21.-

Serine endopeptidases.

based on mapping to UniProt Q92743

UniProtKB Entries (2)

Q9CZU6	CISY_MOUSE Mus musculus Citrate synthase, mitochondrial
Q92743	HTRA1_HUMAN Homo sapiens Serine protease HTRA1

PDB Structure

PDB	3NZI
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Substrate-induced remodeling of the active site regulates human HTRA1 activity. Truebestein, L., Tennstaedt, A., Monig, T., Krojer, T., Canellas, F., Kaiser, M., Clausen, T., Ehrmann, M. Nat.Struct.Mol.Biol.