CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.720 | Alkaline Phosphatase, subunit A | |
3.40.720.10 | Alkaline Phosphatase, subunit A |
Domain Context
CATH Clusters
Superfamily | Alkaline Phosphatase, subunit A |
Functional Family | Alkaline phosphatase |
Enzyme Information
3.1.3.1 |
Alkaline phosphatase.
based on mapping to UniProt P05187
A phosphate monoester + H(2)O = an alcohol + phosphate.
-!- Active at a high pH optimum. -!- Wide specificity. -!- Also catalyzes transphosphorylations. -!- Some enzymes hydrolyze diphosphate (cf. EC 3.6.1.1).
|
UniProtKB Entries (1)
P05187 |
PPB1_HUMAN
Homo sapiens
Alkaline phosphatase, placental type
|
PDB Structure
PDB | 3MK2 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Refined structures of placental alkaline phosphatase show a consistent pattern of interactions at the peripheral site.
Acta Crystallogr.,Sect.F
|