CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.20 | Up-down Bundle |
|
1.20.190 | Delta-Endotoxin; domain 1 |
|
1.20.190.20 | 14-3-3 domain |
Domain Context
CATH Clusters
| Superfamily | 14-3-3 domain |
| Functional Family | 14-3-3 gamma 1 |
Enzyme Information
UniProtKB Entries (1)
| P04049 |
RAF1_HUMAN
Homo sapiens
RAF proto-oncogene serine/threonine-protein kinase
|
PDB Structure
| PDB | 3IQU |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Impaired binding of 14-3-3 to C-RAF in Noonan syndrome suggests new approaches in diseases with increased Ras signaling.
Mol.Cell.Biol.
|
