CATH Domain 3i3tH00

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.10	Roll
	3.10.20	Ubiquitin-like (UB roll)
	3.10.20.90	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1

Domain Context

CATH Clusters

Superfamily	Phosphatidylinositol 3-kinase Catalytic Subunit; Chain A, domain 1
Functional Family	Polyubiquitin-C

Enzyme Information

UniProtKB Entries (1)

UBP21_HUMAN

Homo sapiens

Ubiquitin carboxyl-terminal hydrolase 21

PDB Structure

PDB	3I3T
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	A strategy for modulation of enzymes in the ubiquitin system. Ernst, A., Avvakumov, G., Tong, J., Fan, Y., Zhao, Y., Alberts, P., Persaud, A., Walker, J.R., Neculai, A.M., Neculai, D., Vorobyov, A., Garg, P., Beatty, L., Chan, P.K., Juang, Y.C., Landry, M.C., Yeh, C., Zeqiraj, E., Karamboulas, K., Allali-Hassani, A., Vedadi, M., Tyers, M., Moffat, J., Sicheri, F., Pelletier, L., Durocher, D., Raught, B., Rotin, D., Yang, J., Moran, M.F., Dhe-Paganon, S., Sidhu, S.S. Science