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CATH Classification

Domain Context

CATH Clusters

Superfamily HUPs
Functional Family NH(3)-dependent NAD(+) synthetase

Enzyme Information

6.3.1.5
NAD(+) synthase.
based on mapping to UniProt Q8ZPU5
ATP + deamido-NAD(+) + NH(3) = AMP + diphosphate + NAD(+).
-!- L-glutamine also acts, more slowly, as amido-donor (cf. EC 6.3.5.1).

UniProtKB Entries (1)

Q8ZPU5
NADE_SALTY
Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
NH(3)-dependent NAD(+) synthetase

PDB Structure

PDB 3HMQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
1.9 Angstrom resolution crystal structure of a NAD synthetase (nadE) from Salmonella typhimurium LT2 in complex with NAD(+)
Halavaty, A.S., Wawrzak, Z., Skarina, T., Onopriyenko, O., Peterson, S.N., Savchenko, A., Anderson, W.F., Center for Structural Genomics of Infectious Diseases (CSGID)
To be Published
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