CATH Domain 3hg2B01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.20	Alpha-Beta Barrel
	3.20.20	TIM Barrel
	3.20.20.70	Aldolase class I

Domain Context

CATH Clusters

Superfamily	Aldolase class I
Functional Family	Alpha-galactosidase

Enzyme Information

3.2.1.22

Alpha-galactosidase.

based on mapping to UniProt P06280

Hydrolysis of terminal, non-reducing alpha-D-galactose residues in alpha- D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids.

-!- Also hydrolyzes alpha-D-fucosides.

UniProtKB Entries (1)

P06280

AGAL_HUMAN

Homo sapiens

Alpha-galactosidase A

PDB Structure

PDB	3HG2
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Catalytic mechanism of human alpha-galactosidase. Guce, A.I., Clark, N.E., Salgado, E.N., Ivanen, D.R., Kulminskaya, A.A., Brumer, H., Garman, S.C. J.Biol.Chem.