CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.1620 | YefM-like fold |
|
3.40.1620.60 |
Domain Context
CATH Clusters
| Superfamily | 3.40.1620.60 |
| Functional Family | A disintegrin and metalloproteinase with thrombospondin motifs 3 |
Enzyme Information
| 3.4.24.87 |
ADAMTS13 endopeptidase.
based on mapping to UniProt Q76LX8
The enzyme cleaves the von Willebrand factor at bond 842-Tyr-|-Met-843 within the A2 domain.
-!- Belongs to peptidase family M12.
|
UniProtKB Entries (1)
| Q76LX8 |
ATS13_HUMAN
Homo sapiens
A disintegrin and metalloproteinase with thrombospondin motifs 13
|
PDB Structure
| PDB | 3GHM |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structures of the non-catalytic domains of ADAMTS13 reveal multiple discontinuous exosites for von Willebrand factor
To be Published
|