CATH Classification

Domain Context

CATH Clusters

Superfamily 3.90.1200.10
Functional Family Choline kinase alpha

Enzyme Information

2.7.1.82
Ethanolamine kinase.
based on mapping to UniProt P35790
ATP + ethanolamine = ADP + O-phosphoethanolamine.
2.7.1.32
Choline kinase.
based on mapping to UniProt P35790
ATP + choline = ADP + phosphocholine.
-!- Ethanolamine and its methyl and ethyl derivatives can also act as acceptors.

UniProtKB Entries (1)

P35790
CHKA_HUMAN
Homo sapiens
Choline kinase alpha

PDB Structure

PDB 3F2R
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of human choline kinase alpha in complex with hemicholinium-3
Hong, B., Tempel, W., Rabeh, W.M., MacKenzie, F., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Weigelt, J., Bochkarev, A., Park, H.
To be Published
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