CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
1 | Mainly Alpha |
|
1.10 | Orthogonal Bundle |
|
1.10.238 | Recoverin; domain 1 |
|
1.10.238.10 | EF-hand |
Domain Context
CATH Clusters
| Superfamily | EF-hand |
| Functional Family | Calmodulin 1 |
Enzyme Information
| 2.7.11.18 |
[Myosin light-chain] kinase.
based on mapping to UniProt P11799
ATP + [myosin light-chain] = ADP + [myosin light-chain] phosphate.
-!- Requires calmodulin for activity. -!- The 20 kDa light chain from smooth muscle myosin is phosphorylated more rapidly than any other acceptor, but light chains from other myosins and myosin itself can act as acceptors, more slowly. -!- Formerly EC 2.7.1.117.
|
UniProtKB Entries (3)
| P11799 |
MYLK_CHICK
Gallus gallus
Myosin light chain kinase, smooth muscle
|
| P0DP29 |
CALM1_RAT
Rattus norvegicus
Calmodulin-1
|
| P42212 |
GFP_AEQVI
Aequorea victoria
Green fluorescent protein
|
PDB Structure
| PDB | 3EKJ |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structures of the GCaMP Calcium Sensor Reveal the Mechanism of Fluorescence Signal Change and Aid Rational Design
J.Biol.Chem.
|