CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.40 | Immunoglobulin-like |
|
2.60.40.10 | Immunoglobulins |
Domain Context
CATH Clusters
| Superfamily | Immunoglobulins |
| Functional Family | HLA class II histocompatibility antigen, DRB1-1 beta chain |
Enzyme Information
| 4.1.1.15 |
Glutamate decarboxylase.
based on mapping to UniProt Q05683
L-glutamate = 4-aminobutanoate + CO(2).
-!- The brain enzyme also acts on L-cysteate, 3-sulfino-L-alanine and L-aspartate.
|
UniProtKB Entries (2)
| P04228 |
HA2D_MOUSE
Mus musculus
H-2 class II histocompatibility antigen, A-D alpha chain
|
| Q05683 |
DCE2_RAT
Rattus norvegicus
Glutamate decarboxylase 2
|
PDB Structure
| PDB | 3CUP |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of the MHC class II molecule I-Ag7 in complex with the peptide GAD221-235
To be Published
|