1 keywords

CATH Domain 3cl3E00

CATH Classification

Level CATH Code Description
Class 1 Mainly Alpha
Architecture 1.20 Up-down Bundle
Topology 1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homologous Superfamily 1.20.5.390 L1 transposable element, trimerization domain

Domain Context

CATH Clusters

Superfamily L1 transposable element, trimerization domain
Functional Family NF-kappa-B essential modulator isoform X1

Enzyme Information

UniProtKB Entries (2)

Q76RF1
Q76RF1_HHV8
Human gammaherpesvirus 8
FLICE inhibitory protein
Q9Y6K9
NEMO_HUMAN
Homo sapiens
NF-kappa-B essential modulator

PDB Structure

PDB 3CL3
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structure of a vFlip-IKKgamma complex: insights into viral activation of the IKK signalosome.
Bagneris, C., Ageichik, A.V., Cronin, N., Wallace, B., Collins, M., Boshoff, C., Waksman, G., Barrett, T.
Mol.Cell