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1 keywords

CATH Domain 3ckkA01

CATH Classification

Level CATH Code Description
Class 3 Alpha Beta
Architecture 3.40 3-Layer(aba) Sandwich
Topology 3.40.50 Rossmann fold
Homologous Superfamily 3.40.50.150 Vaccinia Virus protein VP39

Domain Context

CATH Clusters

Superfamily Vaccinia Virus protein VP39
Functional Family tRNA (guanine-N(7)-)-methyltransferase

Enzyme Information

2.1.1.33
tRNA (guanine(46)-N(7))-methyltransferase.
based on mapping to UniProt Q9UBP6
S-adenosyl-L-methionine + guanine(46) in tRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(46) in tRNA.
-!- The enzyme specifically methylates guanine(46) at N(7) in tRNA.

UniProtKB Entries (1)

Q9UBP6
TRMB_HUMAN
Homo sapiens
TRNA (guanine-N(7)-)-methyltransferase

PDB Structure

PDB 3CKK
External Links
Method X-RAY DIFFRACTION
Organism Escherichia
Primary Citation
Crystal structure of human methyltransferase-like protein 1.
Zeng, H., Dong, A., Dobrovetsky, E., Bountra, C., Weigelt, J., Arrowsmith, C.H., Edwards, A.M., Bochkarev, A., Min, J., Plotnikov, A.N., Wu, H.
To be Published
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