CATH Domain 3cdeB04

Superfamily
Functional Family	-

PDB	3CDE
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Novel HCV NS5B polymerase inhibitors derived from 4-(1',1'-dioxo-1',4'-dihydro-1'lambda(6)-benzo[1',2',4']thiadiazin-3'-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 3: Further optimization of the 2-, 6-, and 7'-substituents and initial pharmacokinetic assessments. Li, L.S., Zhou, Y., Murphy, D.E., Stankovic, N., Zhao, J., Dragovich, P.S., Bertolini, T., Sun, Z., Ayida, B., Tran, C.V., Ruebsam, F., Webber, S.E., Shah, A.M., Tsan, M., Showalter, R.E., Patel, R., Lebrun, L.A., Bartkowski, D.M., Nolan, T.G., Norris, D.A., Kamran, R., Brooks, J., Sergeeva, M.V., Kirkovsky, L., Zhao, Q., Kissinger, C.R. Bioorg.Med.Chem.Lett.